CaV1.2 Calcium Channels: Just Cut Out to Be Regulated?
نویسندگان
چکیده
Tight regulation of calcium entry through the L-type calcium channel CaV1.2 ensures optimal excitation-response coupling. In this issue of Neuron, Michailidis et al. (2014) demonstrate that CaV1.2 activity triggers negative feedback regulation through proteolytic cleavage of the channel within the core of the pore-forming subunit.
منابع مشابه
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ورودعنوان ژورنال:
- Neuron
دوره 82 شماره
صفحات -
تاریخ انتشار 2014